FABRICATING SILVER NANOPARTICLES – CURCUMIN – WATER SOLUBLE CHITOSAN COMPOSITE AND EVALUATING ITS CAPACITY FOR BURN TREATMENT
Corresponding Author(s) : Nguyen Ba Trung
UED Journal of Social Sciences, Humanities and Education,
Vol. 5 No. 2 (2015): UED JOURNAL OF SOCIAL SCIENCES, HUMANITIES AND EDUCATION
This paper presents a method for fabricating AgNP – Curcumin – WS chitosan composite and evaluating its capability for burn treatment. The size of AgNP synthesized from AgNO3 using sodium nitatre as a reducing agent was in the range of 16 to 18 nm. The formation of the synthesized AgNP was characterized by means of the UV – Vis method and X-ray diffraction (XRD); the size of the synthesized AgNP was specified via the TEM method. Antibacterial tests against Gram-negative and Gram-positve bacteria showed that the synthesized sample demonstrated significant effects against both Escherichia coli and Staphylococcus aureus. Clinical tests on rabbits resulted in the fact that the burns was dry and disinfected, especially with no scars left after healing, which proved the capability for burn treatment of this material.
Download CitationEndnote/Zotero/Mendeley (RIS)
 Nguyễn Gia Tiến, Nghiên cứu tác dụng của nano bạc điều trị tại chỗ tổn thương bỏng, Báo cáo nghiệm thu đề tài nhánh Nghị định thư - Viện Bỏng Lê Hữu Trác. Hà Nội, 26 – 27.
 M. H. Branton, J. B. Kopp (1999), TGF-beta and fibrosis, Microbes Infect. 1349 – 1365.
 N. H. Chau, N. Q. Buu (2008), et al, Some results in manufacturing of nanosilver and investigation of its application for disinfection- Adv. Nat. Sci and Tech (VAST). 241 – 248.
 Trần Thị Ngọc Dung, Nguyễn Hoài Châu, Đào Trọng Hiền… (2011), Nghiên cứu tác dụng của băng nano bạc lên quá trình điều trị vết thương bỏng, Tạp chí Khoa học và Công nghệ. 4987 – 4992.
 Mahendra R, et al (2009), Silver nanoparticles as a new generation of antimicrobials, Biotechnol. Adv. 76 – 83.
 Entsar S. Abdou, Khaled S.A. Nagy and Maher Z. Elsabee (2008), Extraction and characterization of chitin and WS chitosan from local sources, Bioresource Technology. 1359 – 1367.
 Majeti N.V. Ravi Kumar (2000), A review of chitin and WS chitosan applications, Reactive & Functional Polymers. 1 – 27.
 Jin Y, Ling PX, et al (2007), Effects of WS chitosan and heparin on early extension of burns, Burns. 1027 – 1031.
 Okamoto Y, Shibazaki K, Minami S, et al (1995), Evaluation of chitin and WS chitosan on open wound healing in dogs, J Vet Med Sci. 57851– 57854.
 Kassaee M.Z, et al (2008), -Ray synthesis of starch-stabilized silver nanoparticles with antibacterial activities, Radiation Physics and Chemistry. 1074 – 1078.